Vol. 6 (04) pp. 282-286 DOI: 10.21474/IJAR01/6856

LA LEISHMANIOSE VISC?RALE AU COURS DU LUPUS ?RYTH?MATEUX SYST?MIQUE, UNE NOUVELLE OBSERVATION AVEC REVUE DE LA LITT?RATURE.

, , , , and
  • Centre de virologie, maladies infectieuses et tropicales. H?pital Militaire d?Instruction Mohammed V. Rabat, Maroc.
  • Service de m?decine interne A. H?pital Militaire d?Instruction Mohammed V. Rabat, Maroc.
15 Downloads 130 Views
Crossref

Download Full Paper (PDF)

Abstract

La leishmaniose visc?rale est une forme particuli?rement grave de l?infection par les parasites intracellulaires du genre Leishmania. Bien que c?est une affection immunod?primante, la survenue de la leishmaniose au cours du lupus ?ryth?mateux syst?mique est rarement d?crite. Nous rapportons le cas d?une patiente suivie pour lupus ?ryth?mateux syst?mique, qui pr?sente un tableau de fi?vre prolong?e nue avec discr?te spl?nom?galie. Le bilan biologique confirme la pouss?e de la maladie lupique avec un syndrome inflammatoire sans s?rite. Malgr? un traitement cortico?de et immunosuppresseurs, l??volution est marqu?e par l?aggravation de l??tat g?n?ral, la persistance du syndrome f?brile et l?apparition d?un syndrome d?activation macrophagique. Le m?dullogramme montre des formes amastigotes de leishmania sp. La patiente est trait?e par antimoniate de m?glumine avec bonne ?volution clinique et biologique. Cette observation pose le probl?me du diagnostic de la leishmaniose visc?rale au cours du lupus ?ryth?mateux syst?mique du fait de sa pr?sentation clinique souvent atypique. Le diagnostic doit ?tre ?voqu? devant tout tableau infectieux prolong? inexpliqu? chez un patient atteint de lupus ?ryth?mateux syst?mique m?me en absence de s?jour en zone d?end?mie.

Keywords

How to Cite This Article

Zohour Kasmy, Youssef Akhouad, Ahmed Reggad, Adil Rkiouak, Ali Zinebi and Khalid Ennibi. (2018); LA LEISHMANIOSE VISC?RALE AU COURS DU LUPUS ?RYTH?MATEUX SYST?MIQUE, UNE NOUVELLE OBSERVATION AVEC REVUE DE LA LITT?RATURE., International Journal of Advanced Research (IJAR), 6 (04), 282-286, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/6856

Corresponding Author

zohour kasmy
Hopital militaire d\'instruction Mohammed V. Rabat; Maroc

Article Analytics

References

  1. Chappuis F,Sundar S,?Hailu A,?Ghalib H,?Rijal S,?Peeling RW, et al.Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol 2007;5:873-82.
  2. Gangneux J.-P, Belaz S, Robert-Gangneux F. Mise au point et actualit?s sur la leishmaniose visc?rale m?dit?ranienne. Journal des Anti-infectieux 2015;17:25-28.
  3. Rosenthal E, Marty P, Del Giudice P, Pradier C, Ceppi C, Gastaut JA, et al. HIV and Leishmania coinfection: a review of 91 cases with focus on atypical locations of Leishmania. Clin Infect Dis2000;31:1093-5.
  4. Basset D, Faraut F, Marty P, Dereure J, Rosenthal E, Mary C, et al. visceral leishmaniasis in organ transplant recipients: 11 new cases and a review of the literature. Microbes Infect 2005;7:1370-5.
  5. Van Griensven J, Carrillo E, L?pez-V?lez R, Lynen L, Moreno J. Leishmaniasis in immunosuppressed individuals. Clin Microbiol Infect 2014;20:286-99.
  6. Louzir H, Dellagi K. Les leishmanioses, un mod?le d??tude des interactions h?te parasite; implications pour la maladie humaine. Ann Inst pasteur 1999;10:67-80.
  7. Jallouli M, Frigui M, Marzouk S, Maaloul I, Kaddour N, Bahloul Z. Complications infectieuses au cours du lupus ?ryth?mateux syst?mique: ?tude de 146 patients. Rev Med interne 2008;29:626-31.
  8. Santana IU, Dias B, Nunes EA, Rocha FA, Silva Jr FS, Santiago MB. Visceral leishmaniasis mimicking systemic lupus erythematosus: case series and a systematic literature review. Semin Arthrit Rheum 2015;44:658-65.
  9. Santos Silva AF, Figueiredo Dias JP, Nuak JM, Rocha Aguiar F, Ara?jo Pinto JA, Sarmento AC. Visceral leishmaniasis in a patient with systemic lupus erythematosus. ID Cases 2015;2:102-5.
  10. Wallis PJ, Clarc CJ. visceral leishmaniasis complicating systemic lupus erythematosus. Ann Rheum Dis 1983;42:201-2.
  11. Ravelli A, Viola S, De Bendetti F, Magni Manzoni S, Martini A. visceral leishmaniasis as a cause of unexplained fever and cytopenia in systemic lupus erythematosus. Acta Paediatr 2002;91:246-7.
  12. Marty P, Leli?vre A, Quaranta JF, Suffia I, Detection by western blot of four antigens characterizing acute visceral leishmaniasis due to Leishmania Infantum. Trans R Soc Trop Med Hyg 1995;89:690-1.
  13. Ossandon A, Bompane D, Alessandri C, Marocchi E, Conti F, Valesini G. Leishmania in systemic lupus erythematosis mimicking an exacerbation. Clin Exp rheumatol 2006;24:186-90.
  14. Fern?ndez-Guerrero ML, Aguado JM, Buz?n L, Barros C, Montalb?n C, Mart?n T, et al. Visceral leishmaniasis in immunocompromised hosts. Am J Med 1987;83:1098-102.
  15. Altozano JG, L?pez-G?mez JM, Robles R, Mui?o A, Romero J, Valderr?bano F. Visceral leishmaniasis in systemic lupus erythematosus. Med Clin (Barc) 1987;88(10):417-8.
  16. Braun J, Sieper J, Schulte KL, Thiel E, Janitschke K. Visceral leishmaniasis mimicking a flare of systemic lupus erythematosus. Clin Rheumatol 1991;10:445-8.
  17. Capell S, Aranda M, Colom? A, L?pez R, Pujol R. Visceral leishmaniasis. Ann Rheum Dis 1993;52(7):551.
  18. L?pez-Soto A, L?pez R. Febrile syndrome, splenomegaly and pancytopenia in a 23-year-old male with systemic lupus erythematosus. Med Clin (Barc) 1992;98:510-5.
  19. Granel B, Serratrice J, Swiader L, Gambarelli F, Daniel L, Fossat C, Hesse-Bon?randi S, et al. Crossing of antinuclear antibodies and anti-leishmania antibodies. Lupus 2000;9:548-50.
  20. Castellino G1, Govoni M, Lo Monaco A, Montecucco C, Colombo F, Trotta F. Visceral leishmaniasis complicating a connective tissue disease: three case reports from Italy. Lupus 2004;13(3):201-3.
  21. P?rez Silvestre J, Campos Fern?ndez C, Calvo Catal? J, Gonz?lez Cruz MI, Baixauli Rubio A, Pastor Cubillo D. Unfrequently opportunistic infection in lupus erythematosus with inmunosuppresive treatment. An Med Interna 2007;24:177-8.
  22. Garg S, Kundu M, Dwivedi AN, Meena LP, Varyani N, Iqbal A, et al. Visceral leishmaniasis or systemic lupus erythematosus flare? Case Reports. Immunol 2012;2012:523589.
  23. Celant A, Chichino G, Dal Bello B, Massarotti M, Minoli L, Marasini B. Visceral leishmaniasis, systemic lupus erythematosus and acute hepatitis. Rheumatol Int 2008;29:111-2.
  24. Moore J, Brown K. Sun, sangria and sandflies: Leishmaniasis in an immunosuppressed patient returning from Spain. Travel Med Infect Dis 2013;11:119-22.
  25. Ben Brahim H, Ben Nasr M, Boussaid H, Kooli I, Aouam A, Toumi A, Loussaief C, Chakroun M. Pericardial tamponade revealing systemic lupus erythematosus during the course of atypical visceral leishmaniasis. Pan Afr Med J 2014;18:323.
  26. Sultan S, Irfan SM. Visceral leishmaniasis in an Afghan woman with systemic lupus erythematosus. Blood Res 2014;49:215.
  27. Malezieux-Picard A, Garzaro-Regard M, Pierre M, Fuzibet J.G, Queyrel-Moranne V, Tieulie N. H?mophagocytose: pouss?e lupique ou leishmaniose visc?rale ? Hemophagocytosis : lupus flare or visceral leishmaniosis ? Rev Med Interne 2014;35(2):A102.
  28. Lachaud L, Dereure J , Chabbert E. Optimized PCR using patient blood samples for diagnosis and follow-up of visceral leishmaniasis, with special reference to AIDS patients. J Clin Microbiol 2000;38:236-40.
  29. Antinori S, Calattini S, Longhi E, Bestetti G, Piolini R, Magni C, et al. Clinical use of polymerase chain reaction performed on peripheral blood and bone marrow samples for the diagnosis and monitoring of visceral leishmaniasis in HIV-infected and HIV-uninfected patients: a single-center, 8-year experience in Italy and review of the literature. Clin Infect Dis 2007;44(12):1602-10.
  30. Rosenthal E, Delaunay P, Jeandel P.-Y, Haas H, Pomares-Estran C, Marty P. Le traitement de la leishmaniose visc?rale en europe en 2009. Place de l?amphot?ricine B liposomale. Med Mal Infect 2009;39:741-744.
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.