Vol. 6 (11) pp. 980-984 DOI: 10.21474/IJAR01/8084

MELANOME CHOROIDIEN PRIMITIF : A PROPOS DUNE OBSERVATION ANATOMO-CLINIQUE.

, , , , and
  • serviced?anatomiepathologique, FMPM-UCA ? CHU Mohamed VI 40000 Marrakech Maroc.
  • service de chirurgieophtalmologique,FMPM-UCA ? CHU Mohamed VI 40000 Marrakech Maroc.
22 Downloads 97 Views
Crossref

Download Full Paper (PDF)

Abstract

Choro?dal melanoma (CM) is the most common intraocular malignant neoplasm in adults. The diagnosis is based on histological and immunohistochemical examination.These tumors have a pejorative prognosis and their evolution is marked by the appearance of metastases especially in the liver. Currently, the development of genomic analyzes has led to a better understanding of the molecular mechanisms involved in oncogenesis. Therapeutic management has become much more difficult since the appearance of conservative treatments to keep the eye. We report a new case of choroidal melanoma in a 29-year-old patient diagnosed at the pathology department of the Mohammed VI CHU (Marrakech, Morocco). The aim of this work is to study the anatomo-clinical and evolutionary aspects of this infrequent entity.

Keywords

Article Analytics

References

  1. Albert DM. Principles and Practice of Ophthalmology. In: Albert, Jakobiec, editors. Philadelphia, PA: W.B. Saunders Co; 1994. pp. 3197?8. Ch. 258.
  2. Andreoli MT,? Mieler WF,? Leiderman YI. Epidemiological trends in uveal melanoma. Br J Ophthalmol.2015 Nov;99(11):1550-3. doi: 10.1136/bjophthalmol-2015-306810. Epub 2015. Apr 22.
  3. Jensen OA. Malignant melanoma of the uvea in Denmark 1943-1952, aclinicalhistopathological, and prognostic study.?ActaOphthalmolSuppl (Copenh)?1963;43(Suppl 75):1?220.?[PubMed]
  4. Shields CL, Shields JA, Milte J, De Potter P, Sabbagh R, Menduke H. Uveal Melanoma in teenagers and children: A report of 40 cases.?Ophthamology.?1991;98:1662?6
  5. Ganley JP, Comstock GW. Benign nevi and malignant melanomas of the choroid.?Am J Ophthalmol.?1973;76:19?25.?[PubMed]
  6. Gallagher RP, Elwood JM, Rootman J, Spinelli JJ, Hill GB, Threlfall WJ, et al. Risk factors for ocularmelanoma: Western Canada Melanoma Study.?J Natl Cancer Inst.?1985;74:775?8.
  7. Chang A. E, Karnell L. H, Menck H. R. The national cancer data base report on cutaneous and non-cutaneous melanoma: a summary of 84,836 cases from the past decade. The American college of Surgeons commission on cancer and The American cancer society.?1998;83:1664?78.
  8. Bond J. B, Haik B. G, Mihara F, et al. Magnetic Resonance Imaging of Choroidal Melanoma with and without Gadolinium Contrast enhancement.?1991;98(4):459?66.
  9. American Academy of Ophthalmology, Soci?t?fran?aised?ophtalmologie. Desjardins L, De?Smet?M (Eds). Anatomiepathologique en ophtalmologie, Tumeursintraoculaires. Section?4. Issy-les- Moulineaux : Elsevier-Masson, 2013:267-83
  10. Xavier Sastre-Garau, Marc-Henri Stern. M?lanomes de la choroide?: Aspects histopathologiques et g?n?tiques. Bulletin de la Division Fran?aise de l?AIP n?60-D?cembre 2014?; 59-63.
  11. Mc Lean I. Uveal nevi and malignant melanoma. In?: ??H. Spencer, Ophtalmic pathology, 4?me?dition, Uveal Tract??, WB Saunders, Philadelphie 1996?; 2121-217.
  12. Hawkins BS Collaborative Ocular Melanoma Study Group. The Collaborative Ocular Melanoma Study (COMS) randomized trial of pre-enucleation radiation of large choroidal melanoma: IV. Ten-year mortality findings and prognostic factors. COMS report number 24.?Am J Ophthalmol.?2004;138:936?51.
  13. Kim IK, Lane AM, Gragoudas ES. Survival in patients with presymptomatic diagnosis of metastatic uveal melanoma.?Arch Ophthalmol.?2010;128:871?5.

How to Cite This Article

S.Berrada,A. Belbachir,C. Ahouissouss,A. Ghazza,A. Moutaouakil and H.Rais. (2018); MELANOME CHOROIDIEN PRIMITIF : A PROPOS DUNE OBSERVATION ANATOMO-CLINIQUE., Int. J. of Adv. Res., 6 (11), 980-984, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/8084

Corresponding Author

Sofia Berrada
Doctor
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.