CLINICOPATHOLOGICAL STUDY OF NEOPLASTIC LARYNGEAL LESIONS IN A TERTIARY CARE HOSPITAL IN KASHMIR
- Senior resident , Department of pathology ,Tata Memorial Hospital ,Mumbai.
- Professor and Head , Department of pathology , Govt. Medical College Srinagar.
- Associate Professor Department of ENT and H&NS . Government Medical College, Srinagar.
- Senior resident , Department of pathology , Govt. Medical College Srinagar.
- Lecturer, Department of pathology , Govt. Medical College Srinagar.
34 Downloads
189 Views
Abstract
Background:The larynx is affected by a range of benign and malignant lesions ,on account of its unique position in the upper respiratory tract which makes it vulnerable to many noxious stimuli. This study was undertaken to explore clinicopathological parameters in laryngeal cancers as laryngeal lesions are coming up to be the most common head and neck lesions in Kashmir.
Methods :A one and a half year observational study was done(2015-2017).All layngectomies and biopsies received in the department were studied.
Results: A total number of 68 neoplastic lesions were studied .The neoplastic lesions showed a peak after 50 years. Squamous cell carcinoma was present in 23.5% cases and was the commonest neoplastic lesion ,Moderately differentiated squamous cell carcinoma was the commonest differentiation(66.7%) . The most common site of involvement was the Glottis (62.5%) of cases. Out of the 11 laryngectomies, 3 cases showed perineural invasion,5 cases showed lymphovascular invasion .
Conclusion:Light microscopy and histopathological examination remains the mainstay and gold standard in diagnosing benign and malignant lesions in larynx.
How to Cite This Article
Arshi Beg, Ruby Reshi, Nisar Hussain Dar, Farzana Manzoor, Summiya Farooq and Ambreen Beigh (2019); CLINICOPATHOLOGICAL STUDY OF NEOPLASTIC LARYNGEAL LESIONS IN A TERTIARY CARE HOSPITAL IN KASHMIR , International Journal of Advanced Research (IJAR), 7 (04), 760-766, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/8883
Corresponding Author
Article Analytics
References
- Pampori R, Shamas I, Islam S. Distribution of Head and Neck Cancers in Kashmir Valley. The Internet Journal of Head and Neck Surgery 2009; Volume 4, Number 2.
- Sharma DK, Sohal BS, Bal MS, Aggarwal S. Clinico-pathological study of 50 cases of tumours of larynx. Indian J Otolaryngol Head Neck Surg 2013; 65(Suppl 1): 29-35.
- Ahmad SM. Carcinoma of Larynx. An epidemiological and Pathological study. Journal of Missan Researches 2010; 7(13).
- Shinde KJ, Hashmi SIH. Clinicopathological Study of Laryngeal Masses. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS). 2015; 14 (1): 61-79.
- Chaitanya V, Nikethan B. Clinicopathological Study of Non Neoplastic and Neoplastic Lesions of Larynx. Int J Intg Med Sci 2015; 2(12): 200-205.
- Kumar JS, Bhutia NN, Bhutia TJ, Malik P, Singh M, Devi HP. Malignant Tumors of the Larynx: A Clinicopathological Study of 30 Cases. Middle East Journal of Cancer 2015; 6(2): 71-78.
- Sajad M, Singh JB, Ali S, Chanda N, Ahmed S, Ahmed M, et al. Cancers of the Upper Aerodigestive tract in Kashmir (A Clinicopathological Study). JK Practitioner 2004; 11(1): 17-20.
- Varalakshmi KP, Naik VS, Swapna RS, Sravani P, Padmaja MN. Laryngeal Biopsies with Special Reference to Malignant Tumors: A Histopathological Study. Int J Sci Stud 2016; 4(3): 197-202
- Markou K, Christoforidou A, Karasmanis I, Tsiropoulos G, Triaridis S, Constantinidis et al. Laryngeal cancer: epidemiological data from Νorthern Greece and review of the literature. Hippokratia. 2013; 17(4): 313-8.
- Iovanescu GH, Poenaru M, Doros C, Boruga O. Histopathological prognostic and risk factors in patients with laryngeal neoplasms RJMe 2013; 54(4): 1087?1092
- Mesolella M, Iorio B, Misso G, Luce A, Cimmino M, Iengo M et al. Role of perineural invasion as a prognostic factor in laryngeal cancer. OncolLett 2016; 11(4): 2595?2598.
This work is licensed under a Creative Commons Attribution 4.0 International License.





