Molecular Detection of Some Mutation Which Causes ?-thalassemia in AL-Muthanna Province-Iraq

This study was conducted to detect of mutations which cause ?-thalassemia by ARMS- PCR assay for the first time in Al-Muthanna province – Iraq, during the period from October-2013 up to March–2014. The study diagnosed three types of mutation in ?-thalassemic patients by ARMS- PCR assay (IVS- I-5, Codon 8\9 , Codon15), the highest percent of ?-thalassemic patients mutation is IVS-I-5(53.8 %) followed by Codon 8\9 and Codon15 with percentage (27.6%) and (18.4%) respectively.