10Aug 2019

THE EFFECT OF CHRONIC EXPOSURE TO 900 MHZ RADIOFREQUENCY RADIATION ON CELLULAR COMPOSITION OF THE BONE MARROW IN THE MATURE RATS.

  • Laboratory of agrofood and health, Faculty of sciences and technologies, University Hassan 1er, Settat.Morocco.
  • Laboratory “Polymers, Radiations and Environment”, Faculty of Sciences, University Ibn Tofail, Kenitra Morocco.
  • Laboratory of pharmacology National Agency of Medicinal and Aromatic Plants, Taounate-Maroc.
  • Laboratory of Biotechnology National Agency of Medicinal and Aromatic Plants, B.P.159, Taounate – Morocco.
  • Abstract
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The daily exposureto radiofrequency radiation(RFR) from the wireless communication deviceshas been a subject of debatefor thepast decade, many studies have been carried out to detect possible effectsof the radiofrequency radiationon human and their consequences on human health.The goal of our study was to assess to whetherthe chronic whole-body exposure to non-thermal radiofrequency (RF) radiation from cellular phones could affect the bone marrow cells in mature rats. Twenty-three Wistar rats weighing 116 and 184 g were randomly divided into 4 groupsaccording to time of exposure: control and exposed groups,animals in treatment groups were exposed to 900-MHz RF (217-Hz pulse rate, 2-Wmaximum peak power, SAR 0.873-0.352 w/kg) for: 0h (control), 1h, 2h and 3h daily, 7 days a week for up 15 weeks.. After the period of exposure,bone marrow aspirations were obtained from the femur of all rats.The cell response was assessed by number and type of the bone marrow nuclear cells using our standard laboratory methods. The results revealed that the number of polychromatophilic and acidophilic erythroblast cells in mature rats increased significantly compared with their control group and number of lymphocytes in mature rats decreased significantly compared with its control groupand this effect is less remarkablewith increasing time of exposure.


  1. Galvin, M.J., Ortner, M.J., McRee, D.I.(1982)Studies on acute in vivo exposure of rats to 2450MHz microwave radiation. III. Biochemical and hematological effects. Radiat. Res. 90, 558?563.
  2. Guyton AC. Textbook of Medical Physiology, 10th ed. Philadelphia, PA: WB Saunders CO; 2000 Haider T, Knasmueller S, Kundi M, Haider M. Clastogenic effects of radiofrequency radiation on chromosomes of
  3. Mutat Res 1994;324:65?8.
  4. Irons RI (I991) Blood and bone marrow. In: Haschek WH, Rousseaux CG (eds) Handbook of toxicologic pathology. Academic Press, San Diego, pp 389-419.
  5. Jain NC (1993) Essentials of veterinary hematology, 1st edn. Lea &Febiger Publication, Philadelphia p389?396.
  6. Jain NC (1986) Schalm's Veterinary Hematology. 4th edn. Lea &Febiger Publication, pp 20?80
  7. Jelodar G, Nazifi S, Adelia E. Effect of leaked radiation from microwave oven on bone marrow ofmale rats in pre and post pubertal stage. Shaheed SadoughiUniv Med Sci 2011; 18(6):496-504.
  8. Kumar G,?Wood AW,?Anderson V,?McIntosh RL,?Chen YY,?McKenzie RJ. (2011) Evaluation of hematopoietic system effects after in radiation exposure in rats Int. J. Radiat. Biol., Vol. 87, No. 2, February, pp. 231?240.
  9. Latimer KS, Mahaffey EA, Prasse KW (2003) Veterinary Laboratory Clinical Pathology. 4th edn. Iowa State Press Iowa, pp 3?45.
  10. Trosic I, Pavicic I (2009) Disturbances of cell proliferation in response to mobile phone frequency radiation. ArthHig Rada Toksikol60:109?115.
  11. Trosic I, Busljeta I, Modlic B. (2004b) Investigation of the genotoxic effects of microwave irradiation in rat bone marrow cells: in vivo exposure. Mutagenesis;19:361?4.

[El Idrissi Sidi Brahim Salem, Elarbi Boussaber, El Goumi Younes, Hayat Talbi, Choukri Abdelmajid and Hillali Abderraouf. (2019); THE EFFECT OF CHRONIC EXPOSURE TO 900 MHZ RADIOFREQUENCY RADIATION ON CELLULAR COMPOSITION OF THE BONE MARROW IN THE MATURE RATS. Int. J. of Adv. Res. 7 (Aug). 525-530] (ISSN 2320-5407). www.journalijar.com


EL IDRISSI Sidi Brahim Salem.
Hay El Maati, Rue Ain Ali Moumen N°75, Settat 26000. Morocco.

DOI:


Article DOI: 10.21474/IJAR01/9530      
DOI URL: https://dx.doi.org/10.21474/IJAR01/9530