Vol. 7 (10) pp. 802-806 DOI: 10.21474/IJAR01/9892

SYNTHESIS OF COUMARIN DERIVATIVES BASED ON MELDRUM ACID AND ITS ANALOGUES.

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  • Termez branch of Tashkent State Technical University named after Islam Karimov.
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Abstract

The article studied the interaction of malonic acid and acetic anhydride with ketones, aldehydes of the fatty, aromatic and carbocyclic series (yields from 16 to 76%). Based on experimental and physical data, it is proved that Meldrum acid exists in solutions in the form of an equilibrium mixture of rapidly convertible conformers.

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References

  1. Davidson D., Bernhard A. The Structure of Meldrum?s supposed β - Lactonic acid // J. Amer.Chem.Soc. 1948. - Vol. 70. - P.3426-3428.
  2. N. Kost, I.N. Khaimov, Yu. Dzhurakulov. On the acid of Meldrum and its analogues. Chemistry heterocycle. compounds. - 1975, No. 11. - S.1482-1486.

How to Cite This Article

Amanova N.D, Khaitova.J.M, Ruzieva.B.Y and Boltaev.B.O. (2019); SYNTHESIS OF COUMARIN DERIVATIVES BASED ON MELDRUM ACID AND ITS ANALOGUES., Int. J. of Adv. Res., 7 (10), 802-806, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/9892

Corresponding Author

Amanova,N.D
Termez branch of Tashkent State Technical University named after Islam Karimov
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