LUNG INVOLVEMENT REVEALING MULTIPLE MYELOMA
Y. Amchich
, N. Reguig
, A. Boucaid
, L. El akkari
, A. Zegmout
, H. Souhi
, N. Messaoudi
, H. El ouazzani
, I.A. Rhorfi
and A. Abid
- Department Of Pneumology, Military Hospital Mohamed V Rabat, Morocco
- Department Of Pneumology, Moulay Youssef University Hospital Center Rabat, Morocco
- Department Of Hematology, Military Hospital Mohamed V Rabat, Morocco
- Faculty Of Medicine and Pharmacy, Mohamed V University Rabat, Morocco
- Abstract
- Keywords
- References
- Cite This Article as
- Corresponding Author
Multiple Myeloma (MM) is a relatively rare disease and it presenting outside the bone marrow, known as extra-medullary myeloma (EMM), is rarer still. The lung parenchyma is an especially unusual site of involvement. We report a case in which the myeloma was diagnosed after we discovered the presence of monoclonal plasma cells in the bronchoalveolar lavage fluid (BAL). Analysis of BAL fluid for the presence of plasma cells provides a noninvasive means of establishing the diagnosis. Interstitial lung disease as pulmonary manifestation of multiple myeloma is even rarer only isolated cases with histological proofs have been reported in the literature.
- Touzeau, P. Moreau, How I treat extramedullary myeloma, Blood 127 (8)2015971?976
- S. Kintzer, E.C. Rosenow, R.A. Kyle, Thoracic and pulmonary abnormalities inmultiple myeloma. A review of 958 cases, Arch. Intern. Med. 138 (5) 1978727?730
- Yuan, R. Wieczorek, D.L. Green, P. Cook, H. Ballard, D.J. Araten, Multiplemyeloma involving skin and pulmonary parenchyma after autologous stem celltransplantation, J. Hematol. Oncol. 2 (1) 200948
- T.W. Ma, R.C.L. Lo, Y. Cheng, C.S. Chim, Multiple myeloma presenting as inter-stitial lung disease, J. Clin. Oncol. 29 (6) 2011143?144
- Ravinet, S. Perbet, R. Guieze, et al., Lung postmortem autopsy revealing extra-medullary involvement in multiple myeloma causing acute respiratory distresssyndrome, Case Rep. Hematol. 2014 20141?3
- Kamble, T. Rosenzweig, Diffuse pulmonary parenchymal involvement in multiplemyeloma: antemortem diagnosis, Int. J. Hematol. 83 (3) 2006259?261
- Kamble R, Rosenzweig T. Diffuse pulmonary parenchymal involvement in multiple myeloma: antemortem diagnosis, Int J Hematol. 2006 Apr83(3):259-61.
[Y. Amchich, N. Reguig, A. Boucaid, L. El akkari, A. Zegmout, H. Souhi, N. Messaoudi, H. El ouazzani, I.A. Rhorfi and A. Abid (2019); LUNG INVOLVEMENT REVEALING MULTIPLE MYELOMA Int. J. of Adv. Res. 7 (Dec). 446-449] (ISSN 2320-5407). www.journalijar.com
Department of pneumology,Military Hospital Mohamed V Rabat, Morocco
