Vol. 7 (12) pp. 372-383 DOI: 10.21474/IJAR01/10163

COMPARATIVE MICROANATOMY OF ORGANS OF ANENCEPHALIC & NORMAL FETUSES OF DIFFERENT GESTATIONAL AGE GROUPS

, and
  • Assistant professor, Department of anatomy & neuroscience, Trinity school of medicine, Trinity medical science university, Ratho mill, St Vincent & Grenadies, West Indies
  • Associate Professor, Department of anatomy, Bangalore medical college & research institute, Fort, Bangalore 56002, Karnataka
  • Professor & head, Department of anatomy, Bangalore medical college & research institute, Fort, Bangalore 56002, Karnataka
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Abstract

Background: Anencephaly is Neural tube defect which is a most common birth defects. This was a hospital based case finding study that covered 60 patients with anencephaly & their respective mothers conducted in hospitals in Bangalore Medical College & Research Institute from 2014 to 2017. Methods: The study includes 60 anencephalic fetuses (23 males & 37 females) of 20-30 weeks. The fetuses were examined for external abnormalities & dissected. Dissected fetal kidney, ureter, stomach, suprarenal gland, thyroid gland, pancreas, lung and liver tissues were processed & stained with H&E. Results: Histological study of the anencephalic organs were studied, Stomach was normal in all the cases. Ureter in 98% cases was normal & in 2% cases, illformed muscular layer was seen. Only in 2.2% of cases Suprarenal gland showed rosettes cell tumor which are little rounded grouping of cells found in tumors .Abnormal development of some hepatocytes & hepatic sinusoids was induced by abnormal development of nervous system of anencephalic fetus which was also found.

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How to Cite This Article

Shilpa K, Sumathi Shekar and Priya Ranganath (2019); COMPARATIVE MICROANATOMY OF ORGANS OF ANENCEPHALIC & NORMAL FETUSES OF DIFFERENT GESTATIONAL AGE GROUPS, International Journal of Advanced Research (IJAR), 7 (12), 372-383, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/10163

Corresponding Author

Dr.Shilpa.karkera
Trinity medical science university

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References

  1. Langman Text book of embroyology: In: Medical Embryology, Indian edition, scientific book agency, Calcutta, 1966:75,257,275.
  2. Arey L.B: In: Development anatomy- A textbook & laboratory manual of embrylogy, 7th edition, W.B. Saunders Co, Philadelphia & London, Toppan Co. Ltd, Tokya, 1966.
  3. Lisa Moore, Anencephaly, Journal of Diagnostic Medical Sonography 2010, 26 (6)286-289
  4. Moore KL., Persaud TVN: In: The Developing Brain-Clinically oriented Embryology.6th edition, W.B. Saunders Co, Philadelphia. 1999:419,463.
  5. Chan C, Hsieh WS, Peng SS: Klippel-F eil syndrome plus atretic meningpcele in one identical twin and anencephaly in the other. J Formos Med Assoc 2003: 102 (7): 506-509.
  6. Priya Ranganath, Sayee Rajangam, Perinatology- Journal of perinatal and neonatal care vol 9 (1):43-47, 2007
  7. Ozturk AH, Kurtoglu Z., Tunncel M, Uluutku H, Aktekin M, Comparison of thickness of myocardial fibres of anencephalic and normal human fetuses. Turk J Pediatr 2002:44 (4):330-333.
  8. N Engl J Med 1990; 322:669-674 March 8, 1990 DOI: 10:10056/NEJM 199003083221006.
  9. Dambska M, Taraszewska A, Czwalinska T: A case of Pseudo-aprosencephaly. Folia neuropathol 2002:40 (3):161-164.
  10. AJ Patowary :the fourth incision ?few modifications in autopsy incisions , J Indian acad forensic med 32(3) pg 234-238 ISSN 0971-0973
  11. L IU Jiang ?Zhou Wen ?Jun The Histological observation of liver of Anencephaly fetus Journal of Hubei vocational technical college 2006-03 XGZJ20060302
  12. AB Namnoum ;GM Hutchins Accelerated maturation of the adrenal medulla in anencephaly Elesvier BV 1990;10(6);895-900)
  13. Suelen Costa ,Joao P.M ,Waldemar s Study of ureter structure in Anencephalic fetuses IBJU 2013;39;512-519)
  14. Eliza R George,Shirali S Patel ,Priyanka Sen A unique case of Eosinophilic Pancreatitis? & anencepha ly in the fetuses of Type 1 diabetic mother Gastroenterology research 2011;4;4;174-176)
  15. Kalaycioglu A, Ucuncu Y, Altunkaynak BZ, Altunkaynak ME, Gundogdu C, Keles ON, Unal B, Kaplan S. Stereological evaluation of kidneys of anencephalic & normal foetuses. Renal Failure, 2013; 35 (1): 110-117.
  16. Bocian-Sobkowska J, Wozniak W, Malendowicz LK. Morphometric studies on the development of human thyroid gland in late fetal life. Histol Histopathol, 1997. 12: 79-84
  17. Shantaram K , Sharma A, Sharma M, Comparative microanatomy of suprarenal gland of anencephalic and normal fetuses of different gestational age groups Journal of the Anatomical Society of India?February 2017;65(2)??
  18. Potters pediatric pathology volume 1 & volume 2 second edition
  19. Gupta P, Nain P & Singh J. Anencephaly:A Neural tube defects ?A review, American journal of pharmtech research , 2016; 2(3).t).

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