Vol. 8 (03) pp. 958-962 DOI: 10.21474/IJAR01/10712

STATUS OF VITAMIN D IN CHRONIC HEMODIALYSIS PATIENTS

  • Service De Biochimie, Laboratoire Centrale dAnalyses Medicales, CHU Hassan II, Fes, Maroc.
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Abstract

Vitamin D metabolism disorders are common in chronic hemodialysis patients.The aim f our workis to determine the status of vit D in chronic hemodialysis patients followed at the ElGhassani dialysis center in order to bring out the correlations between this rate and the markers of phosphocalcic assessment. Our study is cross-sectional on 131 Moroccan patients , under periodic hemodialysis. We evaluated the status of vit D , as well as the correlation between the serum 25OHD level and the epidemiological and biological parameters of phosphocalcic metabolism. Our patients had an average of 25 (OH) D at 22.70 +/- 10.48 ng / ml 90.16% of them had a Vitamin D deficiency or deficiency. There was a correlation between the serum 25 (OH) D level and the female sex. The results of this study have shown that Vit D deficiency and deficiency are almost universal in the hemodialysis population, particularly in women in winter.

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References

  1. P et al. Place de la vitamine D native en dialyse. NEPHRO-760 No. of Pages11.
  2. Jean G , Chazot C?. La vitamine D et linsuffisance renale chronique : les douze points essentiels. Medecine Nucleaire xxx (2015) xxx-xxx .
  3. Ishimura E et al:Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure. Kidney Int 55: 1019-1027, 1999.
  4. Reichel H et al: Synthesis in vitro of 1,25-dihydroxyvitamin D3 and 24,25 dihydroxyvitamin D3 by interferon-gamma-stimulated normal human bone marrow and alveolar macrophages.J Biol Chem 262: 10931- 10937, 1987.
  5. Liu PT et al: Toll-like receptor triggering of a vitamin Dmediatedhuman antimicrobial response. Science 311:1770-1773, 2006.
  6. Bour A, Nejjari B?: Connaissance sur la vitamine D?: etat des lieux de la prevalence de l?hypovitaminose D chez la population marocaine?.Annales des sciences de la sante,N15,Vol.1?:24-31?.
  7. Holick MF: High prevalence of vitamin D inadequacy and implications for health. Mayo Clin Proc 81: 353-373, 2006.
  8. Hirani Vet al: Predictors of 25-hydroxyvitaminD status among adults in two British national surveys.Br J Nutr 101: 760-764, 2009.
  9. Mahfoudh H et al :Deficit en calcidiol (25OH vitamine D) chez les dialyses du CHU de Sfax (sud tunisien). http://dx.doi.org/10.1016/j.nephro.2012.07.238.
  10. Guillaume et al. La prescription de vitamine D chez le patient dialyse en pratique clinique. Nephrologie & Therapeutique (2009) 5, 520?532.
  11. M.M et al .Prevalence de la baisse des reserves en vitamine D chez les sujets ? peau noire en hemodialyse periodique vivant ? Dakar (Senegal) :? propos de trente-sept cas.
  12. Gonza?lez EA et al: VitaminD insufficiency and deficiency in chronic kidney disease. Am J Nephrol. 2004 24:503-510.
  13. Delvalle et al:Prevalence of 25(OH) vitamin D insufficiency and deficiency in chronic kidney disease stage 5 patients on hemodialysis. Hemodialysis International 2007 11:315-321.
  14. Lioussfi Z et al?:Evaluation du statut de la vitamine D chez les dialyses chroniques au CHU de Rabat : prevalence du deficit et correlation avec differentes pathologies?. http://dx.doi.org/10.1016/j.nephro.2012.07.220.
  15. Nigwekar et al : Ergocalciferol and cholecalciferol in CKD. Am J Kidney Dis 201260:139-56.
  16. Hewison M et al: 1alpha-Hydroxylase and the action of vitamin D. J Mol Endocrinol 200025:141-8.
  17. Zehnder D et al: Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in the human kidney. J Am Soc Nephrol 199910:2465-73.
  18. Levin A et al:Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: results of the study to evaluate early kidney disease. Kidney Int 200771:31-8.
  19. LaClair RE et al: Prevalence of calcidiol deficiency in CKD: a cross-sectional study across latitudes in the United States. Am J Kidney Dis 200545:1026-33. [63]
  20. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 20133:S1-150.
  21. Bhan I et al: Clinical measures identify vit D deficiency in dialysis. Clin J Am Soc Nephrol 5: 460-467, 2010. doi: 10.2215/CJN.06440909.

How to Cite This Article

Jamai I, El. Boukhrissi F. and Mahmoud M (2020); STATUS OF VITAMIN D IN CHRONIC HEMODIALYSIS PATIENTS, Int. J. of Adv. Res., 8 (03), 958-962, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/10712

Corresponding Author

Jamai I
Service de biochimie, Laboratoire Centrale d’Analyses Médicales, CHU Hassan II, Fes, Maroc.