Vol. 8 (03) pp. 918-924 DOI: 10.21474/IJAR01/10706

EFFECTS OF DRUGS ON SPIKE GLYCOPROTEIN OF SARS-COV 2 IN CONTROL OF COVID-2019

  • Department of Microbiology and Bioinformatics, UTD, Atal Bihari Vajpayee University, Bilaspur (Chhattisgarh), India.
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Abstract

The spike glycoprotein of SARS-CoV 2 is 3849 bp length present from 21536 to 25384 location in genome as per the prediction from FGENESV0 server and is related to mutated SARS genome. The tiny molecular key on SARS-CoV-2 that gives the virus entry into the cell is called a spike protein, or S-protein. The docking results have shown that compounds like Curcumin (Enol form) and Anti-Viral drugs like Ombitasvir with SARS CoV2 has shown best results. Apart with these compounds Curcumin (Keto form), Cholecalciferol (Vitamin D), Ascorbic acid (Vitamin C), 3-isobutyl-1-methylxanthine (in tea), Chloroquine, Eugenol, Theophylline and Caffeine are also shown better results. The compounds provide support for the development of immune system and control SARS-CoV2. The results have shown that turmeric powder, tea and sun light can treat COVID-2019 in natural way.

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How to Cite This Article

Dowluru SVGK Kaladhar (2020); EFFECTS OF DRUGS ON SPIKE GLYCOPROTEIN OF SARS-COV 2 IN CONTROL OF COVID-2019, Int. J. of Adv. Res., 8 (03), 918-924, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/10706

Corresponding Author

Dr.DSVGK Kaladhar
UTD, Microbiology and Bioinformatics, Atal Bihari Vajpayee University, Bilaspu (CG)-495001
Creative Commons Attribution 4.0 This work is licensed under a Creative Commons Attribution 4.0 International License.