HISTOPATHOLOGICAL SPECTRUM OF NON INFECTIOUS GRANULOMATOUS DERMATOSES AT A TERTIARY CARE CENTRE

Granulomatous dermatoses comprise a wide range of etiologically and clinically distinct skin diseases that share a common histology characterized by the accumulation of histiocytes. Non infectious granulomatous dermatoses includes a wide range of lesions like granuloma annulare, rheumatoid nodule, fat necrosis, granulomatous panniculitis. Aim of present study was to study in detail histopathological spectrum of non-infectious granulomatous dermatoses with respect to their age, sex & site. A total of 770 skin biopsies were received out of which 364 belonged to granulomatous skin disorders from which 64 were diagnosed in category of non-infectious granulomatous skin disorders. Special stains were studies wherever indicated. The commonest skin lesion was calcinosis cutis (23.4%) followed by fat necrosis (20.3%), granuloma annulare (18.7%), rheumatoid nodule, sarcoidosis & granulomatous panniculitis each comprising of 3.1%. All lesions showed female preponderance over males. Histopathology remains the gold standard to diagnose all cutaneous granulomatous dermatoses along with good Dermato-histological correlation.