Synthesis, Characterization and Anti-Breast Cancer Activity of some new pyrazole, thiazole, chromene and pyridine derivatives

As a part of ongoing studies in developing new potent antitumor agents. A novel synthesis of 2-cyano-N-(cyclohexyl) acetamide (2) has been reported. 2-Cyano-N-(cyclohexyl) acetamide (2) was utilized as key intermediate for the synthesis of some new pyrazole, thiazole, chromene, thiophene, and pyridine derivatives. The structures of the newly synthesized compounds were confirmed by elemental analysis, IR, 1H NMR, and mass spectral data. Representative compounds of the synthesized products were tested and evaluated as Anti-breast Cancer gents.