GATA3 - IS IT A PROGNOSTIC MARKER IN BREAST CARCINOMA?

GATA binding proteins are among the new prognostic factors being explored. My area of interest is GATA3 to correlate it with tumor size, nodal status ,tumor grade, Estrogen receptor, Progesterone receptor and HER2neu receptors in breast carcinoma patients This was a quantitative correlational study Patient were enrolled using consecutive non probability sampling method. GATA3 was inversely related with tumor size ,nodal status and grade. Estrogen positivity was associated with higher GATA3. However Progesterone and HER2Neu receptors statuses did not show any significant association with GATA3 levels. This study concludes that GATA3 expression can be used as a prognostic marker of breast cancer.