Potential Organoselenium Radiomodifiers against Gamma Radiation Effects
Bruno M.R. Carvalho
, Liliane F. Bauermann
, Samir F. de A. Cavalcante
, Robson B. Freitas
, Helio C. Vital
, Edson R Andrade
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This study is aimed at evaluating the potential radiomodifying properties of the compounds ebselen (C13H9NOSe) and diphenyl diselenide (C6H5Se2C6H5). Phospholipids from chicken egg yolks were gamma irradiated and their concentration of MDA were measured in order to assess radiation damage. The resulting concentrations of Malondialdehyde in the samples were found to decrease with dose, being significantly lower in most cases than the control. Ebselen and diphenyl diselenide were considered potentially effective as positive radiomodifiers.
[Bruno M.R. Carvalho, Liliane F. Bauermann, Samir F. de A. Cavalcante, Robson B. Freitas, Helio C. Vital, Edson R Andrade (2015); Potential Organoselenium Radiomodifiers against Gamma Radiation Effects Int. J. of Adv. Res. 3 (Jan). 0] (ISSN 2320-5407). www.journalijar.com
