IMMUNOPHENOTYPIC PROFILE OF T ACUTE LYMPHOBLASTIC LEUKAEMIA IN A TERTIARY CARE CENTRE - OUR EXPERIENCE
- Senior Resident, Department of Hematopathology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, India.
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Background:Studying the immunophenotypic profile of T-ALL patients in Kashmir and correlation of various demographic factors.
Methods: 36 patients of all age groups were registered for this study of which 35 were included in the analyses.
Result: 82.86% were males and 17.14% were females. 51.43% had common thymocyte T-ALL, 28.57% had pro T-ALL and 20% had mature thymocyte T-ALL. The average age at presentation was 18.60 years. 51.43% were CD1a positive. CD2 was positive in 70.83%. 88.57% were CD5 positive while 100% were positive for CD7. 42.86% were CD34 positive. The average bone marrow blast percentage was 82.43%. The average peripheral blood TLC was 92.73 x 103 cells/cumm.
Conclusion: This is the first study to report immunophenotypic and demographic profile of T-ALL in Kashmir with the aim to increase understanding of the disease and contributing to more suitable treatment options.
[Sumayya Shah and Saleem Hussain Mir (2020); IMMUNOPHENOTYPIC PROFILE OF T ACUTE LYMPHOBLASTIC LEUKAEMIA IN A TERTIARY CARE CENTRE - OUR EXPERIENCE Int. J. of Adv. Res. 8 (Nov). 952-956] (ISSN 2320-5407). www.journalijar.com
Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Kashmir, India 190011
India
