DIAGNOSTICAL AND SOME IMMUNOLOGICAL PARAMETERS OF A TYPICAL PEDIATRIC PNEUMONIA

This study was planned to diagnosis of some bacterial causative agents of atypical pneumonia addition to clinical signs and symptoms and study some immunological biomarkers for pediatric pneumonia.This work isclinically used diagnosed children patients ( n =100 ) of pneumonia were chosen and in addition to (n = 40 ) apparently healthy children as a control group between October 2013 to July 2014. Specific diagnosis is clinically done by consultant physicians for all studied patients. The patients were distributed into three groups according to the age, <1 year (40) patient, 1-3 years (30) patient and 4-5 years(30) patient. By using the indirect immunofluorescent assay IIFA, the results showed that the specific (IgM) antibody were detected in serum of infection patients. Thebacterial agents 29 (29%) from all patients 100 which distributed to four genera Mycoplasma pneumonia(14%), Legionella pneumophilaserogroup1(11%), Coxiella burnetii(2%) and Chlamydophila pneumonia(2%). The WBCs count showed no significant increase at (P<0.05) of concentration in patient groups8.56±3.37cell/cu mm comparison with control8.17±1.83cell/cu mm. A significant increase of neutrophil cells count patients 5.02±2.29cell/cu mm comparison with control 3.87±1.045 in bacterial causes 5.02±2.29 cell/cu mm. Significant increase was shown in lymphocyte cells count of pneumonia patients 2.72±1.85cell/cu mm when camper with control 3.33±0.834cell/cu mm.A highly significant increase in patients C-Reactive Protein (CRP) 9.72±13.24mg/l comparison with control 3.40±1.08mg/l.