LYCOPENE EFFICACY TOWARDS STREPTOZOTOCIN INDUCE COGNITIVE DYSFUNCTION: A PRELIMINARY POSSIBLE FUTURE ALTERNATIVE FOR NEUROLOGICAL AILMENTS

Lycopene, a red-colored carotenoid,established for its antioxidant potentials towards cognitive dysfunction, a predictor of neurological maladies. Plentiful research in arena emphasizing towards formulation advancement and dose adjustment, incliningto impart an edge for lycopene biopotentials, but still leaving a lag. Current preliminary research emphasizes on therapeutic potentials of lycopene over cognitive dysfunction at certain doses established via behavioral models.Lycopene 100mg/kg dose depicted a significant immobility time curtail to 53.33±4.356secs in despair Test (DT), 25.67±2.028 crossing in Light and dark (LD) simulation, and 22.67±1.116 rotations in manual rota-wheels(RW) designrespectively,in contrast to STZ control 83.50±4.766 sec (DT), 14.67±1.764 (RD)and 9.333±1.606(RW) respectively.Lycopene 100 mg/kg dose depicted positive and impressive results against cognitive dysfunction. Prospectively,Lycopene could be utilized as an alternative supplement for neurological diseases.