A COMPARATIVE STUDY OF SERUM TOTAL CHOLESTEROL IN PRE AND POST-CHOLECYSTECTOMY PATIENTS UNDERGOING LAPAROSCOPIC CHOLECYSTECTOMY

Background:Laparoscopic cholecystectomy has many advantages over laparotomy like smaller incisions, reduced surgical trauma, less post-operative pain, faster recovery time, shorter hospital stay, and faster return to normal activities or routine work. So, it is considered as the gold standard for surgical treatment of benign gallbladder disease like cholelithiasis.The aim of this study was to elucidate the association of serum total cholesterol with cholelithiasis patients and effect of cholecystectomy on the same by laparoscopic procedure.

Methodology: This study was conducted prospectively on 109 patients in a tertiary care hospital in eastern Uttar Pradesh, India. From January 2019 to December 2019, patients admitted for cholecystectomy in General surgery ward of this hospital were included in this study. Fasting blood samples of the patients were collected firstbefore surgery and then 12-24 hours after surgery and were analyzed in the biochemistry laboratory of the institute after proper control and calibration, meeting the quality standard of the laboratory. Values of serum total cholesterol thus obtained were compared with each other.

Results: In our study, 84.4% patients were females with mean age of 43.1 years and 15.6% patients were males with mean age of 40.8 years. A reduction in mean value of serum total cholesterol was noted pre-operatively from 221.1 mg/dL to 203.5 mg/dL post-operatively.

Conclusion: From our study, we concluded that laparoscopic cholecystectomy is beneficial in lowering down the serum total cholesterol and hence reduces the risk factors for associated diseases.