Vol. 10 (01) pp. 644-649 DOI: 10.21474/IJAR01/14085

NOVEL SYNTHETIC METHOD FOROZENOXACIN

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  • Discovery Chemistry Solutions, Aragen Life Sciences, Nacharam, Hyderabad, Telangana State, 500076, India.
  • Department of Inorganic and Analytical Chemistry, Andhra University, Visakhapatnam, Andhra Pradesh, 530003, India.
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Abstract

A newsynthetic route has been developed for the total synthesis of ozenoxacin. In this route avoided toxic heavy metals and synthesised the key intermediate_7-bromo-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid by simply insertion of Cyclopropyl amine into 4-oxo-4H-chromene-3-carboxylic acid intermediate, Then the key intermediate carboxylic acidundergoesSuzuki coupling with boronated ester and deacetylation to afford ozenoxacin.

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How to Cite This Article

Srinivasa Rao Inukollu, Pradipta Sinha, Ajay Soni, Arani pal and Nageswara Rao Gollapalli (2022); NOVEL SYNTHETIC METHOD FOROZENOXACIN, Int. J. of Adv. Res., 10 (01), 644-649, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/14085

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SRINIVASA RAO INUKOLLU
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India
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