Vol. 10 (02) pp. 452-457 DOI: 10.21474/IJAR01/14224

HEMODYNAMIC CHANGES IN LOW DOSE INTRATHECAL DEXMEDETOMIDINE AND CLONIDINE AS ADJUVANT TO BUPIVACAINE - A COMPARATIVE STUDY

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  • Senior Resident, Dept of Paediatrics, Tripura Medical College, Hapania, Tripura.
  • Assoc Professor, Dept of Anaesthesiology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra.
  • Professor and HOD, Dept of Paediatrics, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra.
  • Junior Resident, Dept of Biochemistry, Agartala Government Medical College, Agartala, Tripura.
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Abstract

Background : To evaluate the effect of low dose intrathecal dexmedetomidine and clonidine as adjuvant to bupivacaine on hemodynamic parameters of the patients . A total of 60 patients , scheduled for lower abdominal , lower limb and gynaecological procedures were selected to participate in this prospective , randomised double blind study . After injecting the drug time were noted (T0) and the patient were turned to supine position . Preoperative systolic and diastolic blood pressure , Heart rate were noted at specific time interval.

Results : Heart rate , systolic blood pressure , diastolic blood pressure and mean arterial pressure were compared in both the groups and there was no statistically significant difference between the two groups .

Conclusions : Both clonidine and dexmedetomidine as adjuvant to bupivacaine showed fall in heart rate , systolic blood pressure , diastolic blood pressure and mean arterial blood pressure . However there was no statistically significant difference between the two groups in these parameters.  

How to Cite This Article

Chayan Sarkar, Sudha Jain, Sucheta Tidke and Moumita Debnath (2022); HEMODYNAMIC CHANGES IN LOW DOSE INTRATHECAL DEXMEDETOMIDINE AND CLONIDINE AS ADJUVANT TO BUPIVACAINE - A COMPARATIVE STUDY, International Journal of Advanced Research (IJAR), 10 (02), 452-457, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/14224

Corresponding Author

Moumita Debnath
Junior Resident , Dept of Biochemistry , Agartala Government Medical College , Agartala , Tripura.

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