SEDATION IN COLONOSCOPY: WHATTHE EFFECT-SITE CONCENTRATION OF PROPOFOL IN TARGET-CONTROLLED INFUSION FOR WHICH THE ACTBECAMECOMFORTABLE AT THE INTRODUCTION OF COLONOSCOPE?
Hicham Hammadi
, Youssef Halhoul
, Achraf Jeddab
, Hamza Kassimi
, Abdelhamid Jaafari
, Abderrahman El Wali
, Mohammed Meziane
, Abdelouahed Baite
and Mustapha Bensghir
- Department of Anesthesiology and Critical Care, MilitaryTeaching HospitalMohammed V, Faculty of Medicine and Pharmacy of Rabat, Mohammed VUniversity of Rabat, Rabat, Morocco.
- Chief of Anesthesiology Department, MilitaryTeaching HospitalMohammed V, Faculty of Medicine and Pharmacy of Rabat, Mohammed VUniversity of Rabat, Rabat, Morocco.
- Abstract
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Method: Prospective observational study carried out over 5 months, with the objective of determining the effect-site concentration of propofol in target-controlled infusion anesthesia which allows the introduction of a colonoscope under the best conditions.84 patients aged 18 to 71 are included: 38% were male and 46% female, with 57% classified as ASA I and 43% as ASA II.
Results: Among the 84 patients: 47.6% had no history, 11.9% hypertensive, 14.3% diabetic, 21.4% dyslipidemic, 4.8% followed for stable heart failure. Reflex loss concentrations averaged 3.78 ug/mL with a minimum of 2.6 ug/mL and maximum of 4.8 ug/mL.While the target concentrations of the introduction of colonoscope which allows comfort for the gastroenterologist and the patient were on average 5.24 ug/mL with a minimum of 3.4 ug/mL and maximum of 6.8 ug/mL.
[Hicham Hammadi, Youssef Halhoul, Achraf Jeddab, Hamza Kassimi, Abdelhamid Jaafari, Abderrahman El Wali, Mohammed Meziane, Abdelouahed Baite and Mustapha Bensghir (2022); SEDATION IN COLONOSCOPY: WHATTHE EFFECT-SITE CONCENTRATION OF PROPOFOL IN TARGET-CONTROLLED INFUSION FOR WHICH THE ACTBECAMECOMFORTABLE AT THE INTRODUCTION OF COLONOSCOPE? Int. J. of Adv. Res. 10 (Apr). 1068-1070] (ISSN 2320-5407). www.journalijar.com
1. Department of Anesthesiology and Critical Care, Military Teaching Hospital Mohammed V, Faculty of Medicine and Pharmacy of Rabat, Mohammed V University of Rabat, Rabat, Morocco
Morocco
