STUDY OF RADIOGRAPHIC FEATURES OF RENAL OSTEODYSTROPHY IN CHRONIC KIDNEY DISEASE (CKD) AND THEIR CORRELATION WITH CLINICAL AND BIOCHEMICAL PARAMETERS

Background: Although frequently silent, mineral and bone disease (MBD) is one of the most precocious complication of chronic kidney disease (CKD) and is omnipresent in patients with CKD stage 5. In recognition of the identical, our study was designed and conceived to review the Radiographic features of Renal Osteodystrophy in CKD and their correlation with Clinical and Biochemical Parameters thus helping in improving the care and outcomes of kidney disease patients worldwide through promoting coordination, collaboration, and integration of initiatives to develop and implement clinical practice guidelines.

Methods: This Observational study was undertaken on a total of 75 patients (both Male & Female) who have been diagnosed with CKD and attended Emergency/OPD or those who were admitted (IPD) seeking medical attention at SAIMS Hospital, Indore, M.P.

Results: Most patients with belonged to 55 - 65 years of age group with M/F ratio being 1.8:1. Majority belonged to Stage 5. Out of 44 patients of CKD stage 5, 37(77.1%) had bone changes. PTH levels were maximum in CKD stage 5. Osteopenia (low bone density) was the commonest Xray finding by subperiosteal resorption of the phalanges. Other findings include pathological fracture, subchondral sclerosis and soft tissue calcification. The levels of the Biochemical parameters i.e. Low calcium, High Phosphorus and High PTH levels was also positively correlated.

Conclusions: The adoption of a clear definition and an improved classification scheme of CKD - MBD, will help in improving the care and outcomes of kidney disease patients worldwide.