STUDY OF SERUM CALCIUM, CREATININE AND URIC ACID IN HYPOTHYROID PATIENTS

Aim: The study is to determine Serum Calcium, Creatinine and Uric acid levels in hypothyroidism cases.

Materials and methods: A total of 25cases were selected randomly for one year study from SVRRGGH, Tirupati with exclusion criteria (renal disease, bone disease, diabetes mellitus and other medical conditions and patients who are on medication that going to affect purines and mineral metabolism). Sca²⁺, creatinine and SUA were done on Erbachem 5X and thyroid hormones were done chemiluminescence.

Results: The mean values of serum calcium were low and creatinine and SUA levels were high in hypothyroidism cases. The p value is <0.0001 and is considered highly significant and TSH were correlated with this parameters for knowing effect of hypothyroidism on renal function, mineral and purine metabolism.

Conclusion : Hypothyroidism patients need to be regularly evaluated for these parameters, as early detection and correction can prevent the complications associated with this metabolic dysfunction.