ANALYSIS OF CORRELATION OF STROMAL CD10 EXPRESSION INCARCINOMABREASTNOSTYPEWITH HER2/NEU
- Assistant Professor, DepartmentofPathology,Government Mohankumaramangalam Medical College,Salem,/TamilNaduDr.MGRMedicalUniversity,Chennai,India.
Abstract
Background:Breastcancerisoneofthemostcommoncanceramongwomen.Stromaplaysanimportantpathogeneticroleincarcinomaofbreast.Stromalmarkercouldbeusedforassessingtheprognosisofbreastcancer.
Methods:30invasiveductalcarcinomaofbreastNOStypewereselected.Hematoxylinandeosinstainingwasdone.ImmunohistochemistrywasdonewithCD10,andHER2.CD10expressioninstromawasstudiedandstatisticallyanalyzedwithHER2.
Results:strongpositivityforstromalCD10wasobservedin46%(14outof30)ofcases.10outof14(71%)CD10positivecasesshowedHER2/neu positivity.CD10expressionwassignificantlyassociatedHER2/neupositivity.
Conclusions:StromalCD10expressionisdirectly correlatedwithHER2receptorpositivity.CD10couldbeusedasnew prognosticmarkerincarcinomaofbreast.
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How to Cite This Article
S. Ulaganathan, Abu Arshad A. and R. Duraisamy (2022); ANALYSIS OF CORRELATION OF STROMAL CD10 EXPRESSION INCARCINOMABREASTNOSTYPEWITH HER2/NEU, Int. J. of Adv. Res., 10 (07), 212-217, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/15022
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