PHYSICOCHEMICAL PROPERTIES OF SILICA NANOPARTICLES AND HEALTH HAZARDS

Large-scale industrial production and global commercialization of Silica Nanoparticles in recent year had resulted in increased risk of human exposures. However, there is a lack of knowledge on the health and environmental effects of such substances and information on their handling and disposal is also frequently incomplete. The current article, review, the physicochemical properties of the different nanosized silica materials that can affect their interaction with biological systems. The article also discuss the biological mechanisms involve in generating toxicity of nanosilica (both crystalline and amorphous), genotoxicity, immunotoxicity, ecotoxicity, workplace exposure, handling practices and alternatives of disposal of silica aerogels nanoparticle.