GRANULAMATOUS REACTION WITH GIANT CELL IN A NEVUS

Melanocytic nevus is a benign proliferation of the melanocytes. Histological subtypes of nevus include junctional, compound, and intradermal nevi. A 35 year old female presented with a black mole of 1.5 x 1 cm on the right lateral side of the nose since birth. Surgical excision was performed for cosmetic reason. Diagnosis of benign intradermal nevus having chronic granulomatous reaction with giant cells was made. This could be secondary to folliculitis or beginning of regression of nevus. Granulomatous reaction with giant cells in a nevus is an unusual pathological finding. Therefore we believe that it is not uncommon finding and practicing dermatopathologist should be aware of this phenomenon.