PARANEOPLASTIC DERMATOMYOSITIS REVEALING OVARIAN CANCER: ABOUT A CASE

Dermatomyositis (DMs) is a systemic autoimmune disease affecting mainly muscle and skin. It may be associated with cancer in a paraneoplastic setting with a frequency ranging from 18 to 32% [1]. various types of cancer are described in the literature however, the association with gynecological cancers, especially in women, is more frequent. the incidence of ovarian cancer in dermatomyositis in women is 13.3% it is higher than in the general population (1%) [2]. We present the case of a patient with paraneoplastic dermatomyositis, who presented with a typical clinical symptomatology of paraneoplastic dermatomyositis, confirmed by other complementary examinations (creatine phosphokinase (CPK) + EMG (electromyogram) + skin biopsy). Etiological exploration by the ovarian specific tumor marker CA 125, and pelvic ultrasound completed by pelvic MRI oriented the diagnosis towards ovarian adenocarcinoma. Our results suggest that a complete gynecological workup including gynecological clinical examination, CA 125, CA 15-3 and pelvic ultrasound should be routinely performed in any woman over 40 years of age with DM.