ORAL SQUAMOUS CELL CARCINOMA - CASE REPORT

Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx andlarynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity cancers are generally associated with tobacco consumption, alcohol abuse,exposure to environmental pollutants and infection with viral agents, namely HPV and EBV or both, whereaspharynx cancers are increasingly attributed to infection with humanpapillomavirus (HPV), primarilyHPV-16. Despiteevidence of histological progression from cellular atypia through various degrees of dysplasia,ultimately leading to invasive HNSCC, most patients are diagnosed with late-stage HNSCC without a clinically evident pre malignant lesion.