21Aug 2024

A CLINICOHAEMATOLOGICAL STUDY IN PANCYTOPENIA

  • Senior Resident, Department of Pathology, B.J. Medical College, Ahmedabad, India.
  • Senior Resident, Department of Pathology, B.J. Medical College, Ahmedabad, India.
  • Senior Resident, Department of Pathology, Government Medical College, Bhavnagar, India.
  • Professor and Head, Department of Pathology, B.J. Medical College, Ahmedabad, India.
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Objectives:

1.      Tostudythecausesandclinicalpresentationsofpancytopenia.

2.      ToevaluateHaematologicalparametersinpancytopeniaalongwithBoneMarrow Examination.

Methods: AretrospectivestudywasconductedatdepartmentofPathologyfromJuly2017to Feb 2020. 20 cases of pancytopenia were evaluated clinically, along with haematological parameters.

Results:Among20casesstudied,Maximumnumberofcases wasintheagegroupof21 -30 years (40%) with male predominance (1.2%). Most patients present with generalized weakness.Thecommonestbonemarrowfindingwasmegaloblasticerythroidhyperplasia. The commonest cause for pancytopenia was megaloblastic anaemia (60%) followed by aplastic anaemia (25%). Other causes of pancytopenia were hypersplenism, subleukemic leukemia, multiple myloma.

Conclusion: Afterstudyingthese cases in present studywe have come onthe conclusion that the commonest cause of pancytopenia is megaloblastic anaemia. The detailed primary haematologicalinvestigationsofpatientswithpancytopeniahelptodeterminethecauseof the same, which is important for planning further investigation and crucial for treatment purpose.


[Jayshri Vaghani, Nirali Marakana, Himali Tandel and Hansa Goswami (2024); A CLINICOHAEMATOLOGICAL STUDY IN PANCYTOPENIA Int. J. of Adv. Res. (Aug). 355-358] (ISSN 2320-5407). www.journalijar.com


Dr. Jayshri A Vaghani
B.J. medical college, Ahmedabad
India

DOI:


Article DOI: 10.21474/IJAR01/19263      
DOI URL: http://dx.doi.org/10.21474/IJAR01/19263