ANALGESIC & ANTIPYRETIC ACTIVITY PROFILE ON GYMNOSTACHYUM FEBRIFUGUM BENTH A FOLK HERB USED IN FEVER

Introduction:Gymnostachyumfebrifugum Benth. commonly known as Jwaraharasoppu in Kannada used by traditional healers in treating fever. It is a perennial herb commonly found in western ghats and coastal Karnataka. To prove traditional claim of herbal drug experimental activity planned.

Materials & Methods: Brewers yeast induced pyrexia and Eddys hot plate models were used for antipyretic and analgesic activity respectively. Aerial part of the test drug collected and extract prepared. In both the models Wistar albino rats were divided into 4 groups with 6 rats in each group. Group 1- Normal Control, Group 2- Standard with administration of paracetamol (for antipyretic study) and diclofenac (for analgesic study), Group 3 (TED×1) and Group 4 (TED×2) with administration of single dose and double dose of test drug respectively.

Results: Drug has shown significant antipyretic result in both single and double dose of test drug dose when compared to the standard drug. Analgesic activity of test drug has shown more significant result in single dose than double dose.