A COMPARATIVE STUDY OF VISHALADI CHURNA AND NISHA LAUHA IN THE MANAGEMENT OF PANDU

Background: Pandu Roga is a common yet significant disease described in Ayurveda, characterized primarily by vaivarnya (pallor) of the skin, mucosa, and eyes, resembling anemia in contemporary medicine. It is considered a manifestation of Rasa-Rakta Dhatu Kshaya (depletion of rasa and rakta dhatus), and its pathogenesis is deeply rooted in the improper functioning of Agni (digestive fire) and vitiation of Doshas, especially Pitta.The present study evaluates and compares the clinical efficacy of Vishaladi Churna and Nisha Lauha in the management of Pandu Roga.

Materials and Methods:A randomized comparative clinical trial was conducted on two groups of patients diagnosed with Pandu Roga. A total of 98 patients diagnosed with Pandu were enrolled in the study. Out of these, 38 patients discontinued treatment before completion. Group A received Vishaladi Churna, and Group B received Nisha Lauhafor 3 days. Assessments were done before and after treatment using hematological investigations, the FACIT Fatigue Scale, and a standarized Ayurvedic pandutalakshana scoring scale.Results:Both groups showed statistically significant improvement (p < 0.0001) in all hematological parameters and subjective symptoms. Group B (Nisha Lauha) demonstrated superior improvement in Hb% (Ac%), RBC count, and cardinal signs like Panduta (88%) and Daurbalya (90.91%). It also showed greater relief in fatigue-related domains such as "I feel weak all over (83.51%) and I am able to do my usual activities(87.39%). Group A (VishaladiChurna) showed better improvement in symptoms related to social activity limitation and Pindikodweshtana (70.37%).