A PROSPECTIVE OBSERVATIONAL STUDY ON PREVALNCE EFFECTIV NESS AND SAFETY OF PHARMACOLOGICALTHERAPY IN PATIENTS WITH BRONCHIALASTHMA.

Aim: To analyze the effectiveness of drugs for the management of bronchial asthma. To determine the prevalence of patients diagnosed with asthma. To study in-depth knowledge of the disease in order to improve asthma management in adults.

Methodology: An observational study was conducted over a period of six months, involving analysis of prescriptions from the Internal Medicine Department. Data were collected using a structured patient data collection form to evaluate diagnosis and treatment approaches for asthma.

Results: The study included patients across various age groups, with the majority affected being adults aged 41 60 years. The leading cause of asthmatic conditions was found to be allergens (38%), followed by smoking, environmental, and genetic factors. The effectiveness of treatment was monitored using spirometry, peak expiratory flow rate, and type of therapy administered.The therapy primarily included:

ICS (Inhaled Corticosteroids)

SABA (Short-Acting Beta-Agonists)

Combination therapies: ICS+SABA and ICS+LABA (Long-Acting Beta-Agonists)Among the patients:

62% were prescribed combination therapy. Of these, 39% showed a favorable response, while 23% showed no significant improvement.

38% were prescribed SABA therapy alone. Of these, 33% showed significant improvement, while 5% showed no response.

Conclusion: It was observed that combination therapy is safe and effective for treating mild to moderate exacerbations of asthma. SABA alone was found to be effective in managing moderate to severe exacerbations. Therefore, both strategies are beneficial in the effective treatment of asthma.