ANTI-ANGIOGENIC EFFECT OF SACCOSTREA CUCULLATA (SISI) IN VARYING DOSES TO ANAS PLATYRHYNCHOS DOMESTICUS (ITIK) CHORIOALLANTOIC MEMBRANE (CAM) ASSAY
N. Patawaran
, D. Borres
, Dagun
, D. Gemoto
, G.M Liao
, C.I. Revidad
, L.E Veloso
, J.A Erese
, J.V.P Jalocon
, K.E Buno
, C.L Awitan
, J.B Milca
, P.A.B Tordesillas
and S.H Rivera
- National University - Mall of Asia.
- School of Allied Health, Department of Medical Technology.
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This study examines the Saccostrea cucullata (Sisi) extract's anti-angiogenic effectiveness with the use of varying doses administered into Anas platyrhynchos domesticus (Itik) using Chorioallantoic Membrane (CAM) Assay. The study used an experimental design to assess the extract's efficacy compared to a negative control group and to determine the minimum dose required for observable effect, such various doses are: 20 mg/mL, 30 mg/mL, and 50 mg/mL. Saccostrea cucullata (Sisi) extract showed significant anti-angiogenic activity, with the strongest inhibition of blood vessel growth observed at the highest dose (50 mg/mL). It implies that Saccostrea cucullata (Sisi) extract could be used therapeutically to prevent the formation of new blood vessels in diseases such as cancer, which cause the development of abnormal blood vessels.
[N. Patawaran, D. Borres, Dagun, D. Gemoto, G.M Liao, C.I. Revidad, L.E Veloso, J.A Erese, J.V.P Jalocon, K.E Buno, C.L Awitan, J.B Milca, P.A.B Tordesillas and S.H Rivera (2025); ANTI-ANGIOGENIC EFFECT OF SACCOSTREA CUCULLATA (SISI) IN VARYING DOSES TO ANAS PLATYRHYNCHOS DOMESTICUS (ITIK) CHORIOALLANTOIC MEMBRANE (CAM) ASSAY Int. J. of Adv. Res. (Jun). 766-775] (ISSN 2320-5407). www.journalijar.com
National University - Mall of Asia
Philippines
