MICROWAVE SYNTHESIS, SPECTRAL AND ANTIMICROBIAL STUDIES OF SOME SCHIFF BASE METAL COMPLEXES

Eco-friendly synthesis and green applications are continuously being explored by researchers all over the world. The numerous research pieces of evidence that microwave technology is a sophisticated tool for both synthesis and leading applications of Schiff base compounds. The greener approach is prioritized over the conventional synthesis because of its environment friendly less energy consuming, less time consuming, less hazardous compounds synthesis with low cost. Some new Schiff base complexes of VO(IV) and Co(II) derived from 4-dimethyl aminobenzaldehyde with 3, 4-dichloroaniline (DCA) have been synthesized by conventional as well as microwave methods and characterized by elemental analysis, FT-IR, ESR and molar conductance. The complexes are colored and stable in air at room temperature. The Schiff base and metal complexes show a good activity against the bacteria; E. coli, S. aureus, S. fecalis and fungi A. niger, T. polysporum. The antimicrobial results also indicate that the metal complexes are better antimicrobial agents as compared to the Schiff base. These observations show that the majority of the complexes are more active than their Schiff base ligand. The higher inhibition zone of metal complexes than that of the ligand can be explained on the basis of Overtones concept and Chelation theory. The findings of the bactericidal and fungicidal investigation of the compounds against the opportunistic pathogens reveal that the synthesized compounds have antipathogenic activity.