BIOFILM OF STAPHYLOCOCCUS AUREUS ON DIFFERENT DENTURES MATERIALS

A common opportunistic infection, Staphylococcus aureus, is remarkably adept at forming biofilms on abiotic and biological surfaces, including several kinds of dental prosthesis materials.Antimicrobial resistance, systemic infections, and denture stomatitis are all seriously threatened by the development of biofilm on denture surfaces in the oral environment.The prevalence of denture stomatitis has significantly increased in recent years, especially among denture users.An erythematous reaction on the oral mucosa that spreads to the boundaries of the maxillary denture bearing area is a frequent inflammatory reaction with a multifactorial origin that typically occurs in the oral cavity. Medical extracts with antibacterial action against oral pathogens have recently been presented as a less harmful and safer treatment option for denture stomatitis. It is critical to reduce the risk of both local and systemic infections in immune compromised cancer patients with maxillary abnormalities, according to the findings of this literature study. Determining how saliva affects microbial adherence to obturator materials is also crucial, as is creating materials with longer lifespans and surface properties that encourage less microbial attachment than existing materials. Highlighting several facets of S. aureus biofilm development and its overall architecture, as well as its constituent parts, clinical consequences, and involvement in pathogenesis and drug resistance, is the aim of this review. Along with discussing numerous tactics that can be utilized to inhibit and eradicate S. aureus biofilm, the review also covers the many methodologies used in the qualitative and quantitative investigation of S. aureus biofilm.