Purification and characterization of a novel anticancer peptide derived from cicer arietinum.
- Department of Biotechnology, Madras University, Guindy Campus Chennai – 6000 25, Tamil Nadu -India.
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Abstract
The aim of the study was to identify the novel peptide from Cicer arietinum seeds and investigate its anticancer activities. The Chymotrypsin was applied for enzymatic hydrolysis. Chymotrypsin hydrolyzates, further purified using a Fast-performance liquid chromatography (FPLC) method, which showed cytotoxicity activity on HeLa cancer cells. Finally, a novel anticancer peptide was purified. The peptide from cicer arietinum effectively induced apoptosis on HeLa cancer cells.
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Ganesan Vijayansiva and Ramarajan Sivasankaran (2015); Purification and characterization of a novel anticancer peptide derived from cicer arietinum., International Journal of Advanced Research (IJAR), 3 (08), 276-280, ISSN 2320-5407.
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