PLATELET CONCENTRATES IN DENTISTRY: BIOLOGICAL AND CLINICAL INSIGHTS A NARRATIVE REVIEW RUNNING PLATELET CONCENTRATES IN DENTISTRY
Camila Roberta Nepomuceno Atripoli
, Camilla Jusevicius Arouche Alves Ferreira
and Sandra Regina Candidoda Silva
- DDS; Specialist in Implant Dentistry; MSc Candidate in Healthcare Management, St. Francis College, New York, USA.
- DDS; Specialist in Implant Dentistry; MSc in Temporomandibular Dysfunction and Orofacial Pain, Sao Leopoldo Mandic, Brazil.
- DDS; Specialist in Orthodontics, FAMOSP; Specialist in Implant Dentistry, Brazil.
- Abstract
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Background: Platelet concentrates, including platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and leukocyte- and platelet-rich fibrin (L-PRF),are autologous biomaterials used to enhance tissue regeneration in dentistry.
Objective: To review the biological mechanisms, technical protocols, and clinical applications of platelet concentrates, with emphasis on PRF and its advanced formulations.
Methods: This narrative review synthesizes current literature on PRP, PRF,A-PRF,i-PRF,and C-PRF, with focus on centrifugation parameters, tube materials, and clinical outcomes in oral surgery, implantology, periodontology, and endodontics.
Results: Evidence indicates that PRF accelerates wound healing, promotes angiogenesis, and enhances bone regeneration; innovations such as A-PRF+ and i-PRF suggest improved growth factor release and wider clinical versatility.
Conclusions: PRF and its derivatives are cost-effective, autologous biomaterials with broad applications in dentistry; future research should prioritize protocol standardization and integration with regenerative technologies.
[Camila Roberta Nepomuceno Atripoli, Camilla Jusevicius Arouche Alves Ferreira and Sandra Regina Candidoda Silva (2025); PLATELET CONCENTRATES IN DENTISTRY: BIOLOGICAL AND CLINICAL INSIGHTS A NARRATIVE REVIEW RUNNING PLATELET CONCENTRATES IN DENTISTRY Int. J. of Adv. Res. (Oct). 351-354] (ISSN 2320-5407). www.journalijar.com
