FIBROMATOSIS OF UNUSUAL SITES-TWO CASE REPORTS

Fibromatosis is a group of tumors characterized by proliferation of fibroblasts and myofibroblasts that grow infiltratively but do not metastasize. Mesenteric fibromatosis itself is a rare entity, comprising less than 0.03% of all tumors, while scrotal fibromatosis is exceedingly uncommon, with fewer than 50 cases reported worldwide. The spectrum includes superficial and deep type based on location however both share similar histology but different molecular characteristics. Fibromatosis shows bland spindle cells arranged in long sweeping fascicles within a collagenous, infiltrative stroma without significant atypia or necrosis. Hallmark feature is strong nuclear beta catenin positivity adding distinction from reactive fibroblastic lesions.We are presenting two cases of fibromatosis arising at the unusual sites-one superficial and one deep, describing their clinicopathological features and discussing the pertinent differential diagnosis.