Vol. 13 (11) pp. 1700-1707 DOI: 10.21474/IJAR01/22305

EVALUATION IN VITRO DE L ACTIVITE VERMICIDE DE GYMNEMA SYLVESTRE RETZ. ET TACAZZEA APICULATA OLIV., DEUX PLANTES UTILISEES AU NIGER DANS LE TRAITEMENT DES MALADIES PARASITAIRES

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  • Laboratoire des Substances Naturelles, Faculta des Sciences et Techniques, Universita Abdou Moumouni, BP 10662, Niamey, Niger.
  • Faculta des Sciences de la Santa, Abdou Moumouni University, Niamey, Niger.
  • Dapartement de Biologie, Faculta des Sciences et Techniques de l Universita Abdou Moumouni de Niamey, BP 10662 Niamey, Niger.
  • Universita Dan Dicko Dan Koulodo de Maradi, Niger.
  • Universita de Bayreuth, Allemagne.
  • Universita Andra Salifou de Zinder, Niger.
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Abstract

Helminthiases represent a major public health challenge. Their prevalence remains particularly high in developing countries within tropical regions, where climatic conditions, poor hygiene, and socio-economic precariousness favor their spread. The present study aimed to evaluate in vitro the vermicidal activity of aqueous and hydroethanolic extracts of Gymnemasylvestre and Tacazzeaapiculata, two medicinal plants from Niger, using Lumbricusterrestris as the animal model. The phytochemical profile of the aqueous and hydroethanolic extracts was determined by tube reactions according to standard characterization methods. Biological assays were conducted at concentrations of 40, 50, and 60mg/mL, with albendazole (40mg/mL) serving as the reference substance. Parameters considered included paralysis time and lethal time. The results revealed a dose-dependent vermicidal activity for both aqueous and hydroethanolic extracts of the two plant species.

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How to Cite This Article

Issoufou Yolidja, Daouda Alhousseini, Rabi Chaibou, Djibo Alfa Keita, Idrissa Moussa, Neino Raba Garba, Biraima Ahmadou, Tilmanmuch and Lamine Mahaman Moustapha (2025); EVALUATION IN VITRO DE L ACTIVITE VERMICIDE DE GYMNEMA SYLVESTRE RETZ. ET TACAZZEA APICULATA OLIV., DEUX PLANTES UTILISEES AU NIGER DANS LE TRAITEMENT DES MALADIES PARASITAIRES, Int. J. of Adv. Res., 13 (11), 1700-1707, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/22305

Corresponding Author

Issoufou YOLIDJE
Laboratoire des Substances Naturelles, Facult des Sciences et Techniques, Universit Abdou Moumouni, BP 10662, Niamey, Niger.
Niger
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