EFFICACY OF ALB-PRF AS ADJUNCTIVE TO NON-SURGICAL PERIODONTAL THERAPY IN MANAGEMENT OF STAGE II PERIODONTITIS
- Oral Medicine, Periodontology, Diagnosis and Oral Radiology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt.
- Clinical Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Abstract
Objective: This research evaluates the clinical effectiveness of local subgingival delivery of injectable extended platelet-rich fibrin (Alb-PRF) compared withmechanical debridement (MD) alonefor the treatment of stage II periodontitis.
Subject and Methods: Thirty patients diagnosed with stage II periodontitis through clinical and radiographic screening were randomly divided into two groups (each group; n=15): group I was treated with MDin combination with Alb-PRF as a local drug delivery (LDD) and group II receivedMD only. Local applications of Alb-PRF during the second visit. Periodontal measurement including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL) were recorded at baseline, three months and six months after MD.
Results: Clinical outcomes showed Alb-PRF group highly significant improvement in PD reduction and CAL gain measurement compared to group II at three and six months of therapy.
Conclusion: The adjunctive incorporation of Alb PRF with MDsubstantially improves the outcomes of non-surgical periodontitis treatment, leading to significantly better periodontal health.
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How to Cite This Article
Nawal Hamza Khalaf, Hesham Mohamed El-Sharkawy, Laila Ragab Sidky, Nancy Hussein and Eman S. Elhennawy (2026); EFFICACY OF ALB-PRF AS ADJUNCTIVE TO NON-SURGICAL PERIODONTAL THERAPY IN MANAGEMENT OF STAGE II PERIODONTITIS, International Journal of Advanced Research (IJAR), 14 (02), 1121-1128, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/22834
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