Oxidative Stress (OS) Impaired Female Fertility
- Assist Professor- Biotechnology research center/ University of AL- Nahrain.
- Assist Professor- College of Sciences/ University of Babylon.
- Lecturer –Institute of Genetic Engenering and Biotechnology for Postgraduate/ University of Baghdad.
- Abstract
- How to Cite This Article
- Corresponding Author
Elevation of oxidative stress suggested cause infertility in female with unexplained infertility. Aim of this project to study who the excess of oxidative stress cause impaired female infertility by effects on antioxidants enzymes activity. Blood samples collected from 40 females with unexplained infertility and from 20 female fertility to measured oxidative stress by protein peroxidase (PPO), lipid peroxidase (LPO) and activities of antioxidant enzymes: glutathione peroxidase (GPX), superoxide dismutase (SOD).Significant elevation in levels of oxidative stress biomarkers in female with unexplained infertility represented by increased levels of PPO and LPO (82.63+10.73; 63.84+9.51) when compared with fertile females (61.52+8.66; 42.67+7.05) respectively. While the results show significant decrease in activity of antioxidants enzymes represented by GPX and SOD in female with unexplained infertility (9.47+1.56; 14.33+3.58) compared with fertile females (12.65+3.02; 20.09+5.42) respectively. We concluded from this study that the elevation of oxidative stress in female with unexplained infertility cause disturbances in activity of antioxidants enzymes and may be cause infertility in females, recovery this relationship help to treatment the female with unexplained infertility and with increase the Oxidative stress by administration of antioxidants as drugs or plants extracts.
Hazim Ismail Abdulbari ALL-Ahme, Hussein Jassim Obade, Rasha Abdul-Hussein Mahood (2015); Oxidative Stress (OS) Impaired Female Fertility, Int. J. of Adv. Res., 3 (11), 274-278, ISSN 2320-5407. DOI URL: https://dx.doi.org/
