Antifungal Activity of Clove Oil On Dermatophytes and Other Fungi

The incidence of fungal infections especially dermatophytosis has been observed increasing worldwide. The resistance of some species of fungi to antifungal drugs, high treatment costs and toxic effect of current drugs, all have encouraged the members of research for alternative natural compounds such as essential oils. The present study was carried out to evaluate the antifungal activity of Clove oil in vitro by agar disk diffusion method at different dilutions (0, 10, 20, 50, and 100%) on the isolated fungi (Trichophyton mentagrophytes, Microsporum canis, Aspergillus flavus and Candida albicans), and confirmed the results through application of Clove oil on cows affected with dermatophytosis. The results concluded that, T. mentagrophytes and M. canis were the most prevalent isolates and Clove oil had a strong antifungal activity against tested isolated fungi especially against Dermatophytes spp in vitro and effectively as a topical treatment in cows with dermatophytosis .