SYNTHESIS OF 1-(4-PYRIDINE) IMINO-5-SUBSTITUTED DITHIOBIURETS

Recently in this laboratory, a direct, suitable and simple method for the synthesis of 1-(4-pyridine)imino-5-substituted dithiobiurets (Va-e) was developed. A novel series of 1-(4-pyridine)imino-5-substituted dithiobiurets (Va-e) was synthesized by the interacting 3-(4-pyridine)iminothiocarbamide (IIIa) with various isothiocyanates (IVa-e) in acetone-ethanol medium on water bath. The reaction mixture was filtered in hot conditions, after distillation of excess solvent, brown coloured crystals were obtained, recrystalised from ethanol. The structure of the synthesized compounds was justified on the basis of chemical characteristics, elemental and spectral analysis.