Synthesis, Reactions and Biological Evaluation of Novel 7-Thioxo-pyrido[2,3-d][1,2,3]triazine Derivatives Bearing Sulfonamide Moiety
- Department of Chemistry, Faculty of Science, Al-Azhar University, Assiut 71524, Egypt,
- Department of Chemistry, Faculty of Science and Arts of Baljurashi, Albaha University, Saudi Arabia.
- Department of Chemistry, Faculty of Science and Arts of Qelwa, Albaha University, Saudi Arabia.
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Abstract
7-Thioxopyrido[2,3-d][1,2,3]triazine derivative bearing sulfonamide moiety was synthesized and reacted with different reagents to afford thieno[3',2':5,6]pyrido[2,3-d][1,2,3]triazines, oxazinothienopyrido-triazines, pyrimidothienopyridotriazines, pyridazinothienopyridotriazines, pyrazolopyridotriazin-6-amine and pyridazinopyrazolopyridotriazines. The biological evaluation of Sixteen of the newly synthesized compounds was screened as antimicrobial compounds.
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Mohamed A. M. Gad-Elkareem and Ismail M. M. Othman (2016); Synthesis, Reactions and Biological Evaluation of Novel 7-Thioxo-pyrido[2,3-d][1,2,3]triazine Derivatives Bearing Sulfonamide Moiety, Int. J. of Adv. Res., 4 (01), 1689-1700, ISSN 2320-5407.
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