One-step synthesis of modified Fe3O4 nanoparticles with enhanced magneticproperty.

A novel one-step synthesis protocol has been developed to reduce the modification reaction time while preserving the saturation magnetization of the Fe3O4magnetic nanoparticles (MNPs). A modified co-precipitation method was employed to synthesize Fe3O4MNPs in an aqueous solution. Surface modification was carried out using citric acid and polyethylene glycol and their dendrimers as biocompatible modifier. Vibrating sample magnetometery ensured a higher saturated magnetization of modified MNPs compared with unmodified MNPs. The spinal structure of Fe3O4MNPs remained intact, verified using X-ray Diffractometery. Surface morphology and the size of modified particles were examined using Transmission Electron Microscopy and X-ray Difractometery. It was observed thatthe proposed synthesis method reduced the modification reaction time dramatically with high magnetic saturation level. The proposed method eliminated the post modification steps such as particle separation, purification, dispersion of synthesized nanoparticles in the reaction media used in conventional procedures.