A facile one pot synthesis of pyrazolyl pyrimidines through multcomponent reaction
- Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi -613 503 India.
- Department of Chemistry, Periyar EVR College, Tiruchirappalli-620 023 India.
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Abstract
A series of new pyrimidine derivatives containing pyrazole moiety were designed and synthesized. In addition, various substituents were introduced in to the entering pyrazole aldehyde ring and ?-keto ester with the purpose of exploring the influence of substituent on anticancer activity by regulating the electronic and steric effects. The synthesized compounds were characterized by various spectroscopic techniques.
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Manickam. Pramesh, Selvaraj. Jayanthi, Ragunathan.Venkatachalam and Bathey. R. Venkatraman. (2016); A facile one pot synthesis of pyrazolyl pyrimidines through multcomponent reaction, International Journal of Advanced Research (IJAR), 4 (04), 995-1001, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/271
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