Is There a Relationship Between Histopathological Features of Acute Appendicitis and Preoperative Acute Inflammatory Markers?

Acute appendicitis is a common surgical emergency, mainly clinically diagnosed with adjuvant laboratory tests, but a histopathologic study is the gold standards for diagnosis. A prospective study of fifty five cases of clinically diagnosed and surgically treated acute appendicitis investigated for preoperative acute inflammatory markers; total white blood cell count(WBC), neutrophils percentage, and C-reactive protein(CRP) to assess the accuracy of the laboratory tests and relationship with severity of pathological changes. CRP and neutrophils percentage were found to be significantly (p value ?0.05) associated with the severity of pathological changes as compared to normal appendicectomies unlike total WBC count that showed no significant difference among pathologically normal and abnormal cases.