ANALGESIC AND ANTIPYRETIC ACTIVITIES OF HAMELIA PATENS LEAF ON ETHANOLIC EXTRACTION IN ANIMAL MODELS.
- Lecturer, Andhra Loyola College, Vijayawada.
- Dean and Professor in Basic Sciences, Avalon University School of Medicine, Curacao-Dutch, Netherlands, Central America.
- Principal St. Xavier Institute of Pharmaceutical Sciences, Phirangipuram.
- Principal Vasavi College of Pharmacy, Tadepalligudem.
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Abstract
The present study investigates the analgesic and antipyretic effects of Hamelia patens leaves on ethanolicextraction.In order to assess the analgesic effects by Formalin induced writhing response model. However at the doses of 50-200 mg/kg analgesic activities were observed in the early and late phases of formalin induced paw licking test in rats. The latency in the hot plate test was increased from 2.2 + 0.3 to 5.7 + 0.3 second (P < 0.05). Likewise, the early and the late phases of formalin test were reduced from 7.4 + 9.4 and 57.8 + 8.4 to 36.6 + 4.4 and 29.2 + 4.4 second respectively.The result confirms the analgesic and antipyretic activities of Hamelia patens leaf extract. We recommended further research on this plant leaves for possible isolation and characterization of the various active chemical substances which has the toxic and medicinal values.
How to Cite This Article
B. Vijay Raj, M.V.RAGHAVENDRA Rao, K. Raj Kumar and K. Srinivas. (2016); ANALGESIC AND ANTIPYRETIC ACTIVITIES OF HAMELIA PATENS LEAF ON ETHANOLIC EXTRACTION IN ANIMAL MODELS., International Journal of Advanced Research (IJAR), 4 (05), 961-966, ISSN 2320-5407. DOI: https://doi.org/10.21474/IJAR01/450
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