CD30 AND p53 EXPRESSION BY IMMUNOHISTOCHEMISTRY IN DLBCL AND ITS ASSOCIATION WITH CELL OF ORIGIN CLASSIFICATION AND OTHER PROGNOSTIC VARIABLES-A RETROSPECTIVE STUDY
- Manipal Academy of Higher Education (MAHE)
Thesis details
- Submitted by
- Dr. Aadhya Sharma
- University
- Manipal Academy of Higher Education (MAHE)
- aadhya_s@yahoo.com
- Supervisor
- Dr. RANJINI KUDVA,
- Year of award
- 2023
- Awards
- DOCTOR OF MEDICINE (MD) IN PATHOLOGY
Summary of Thesis
The most common type of Non-Hodgkin's lymphoma is diffuse large B cell lymphoma (DLBCL), which accounts for about 30% to 40% of adult NHL cases.(1) DLBCL is a clinically, biologically and molecularly heterogeneous disease entity. Two molecularly distinct types of DLBCL with gene expression patterns indicative of various stages of B-cell development were discovered by gene expression profiling in 2000.(2) These were Germinal Center B-cell like DLBCL (GCB) subtype with a gene expression pattern characteristic of normal germinal center B-cells and Non-Germinal Center like DLBCL (non-GCB) subtype with a gene expression pattern characteristic of in vitro activated peripheral blood B-cells. So non-GCB subtype is also referred to as Activated B-cell like DLBCL (ABC) subtype.
Thesis chapter scheme
<p class="ql-align-justify"><strong>1. </strong>General Introduction</p><p class="ql-align-justify">2. The Research Focus</p><p class="ql-align-justify">3. Review of Other Work Done</p><p class="ql-align-justify">4. Research Methods </p><p class="ql-align-justify">5. Results of Research Analysis </p><p class="ql-align-justify">6. Conclusion </p><p><br></p>
How to Cite This Thesis
Dr. Aadhya Sharma (2024); CD30 AND p53 EXPRESSION BY IMMUNOHISTOCHEMISTRY IN DLBCL AND ITS ASSOCIATION WITH CELL OF ORIGIN CLASSIFICATION AND OTHER PROGNOSTIC VARIABLES-A RETROSPECTIVE STUDY, Manipal Academy of Higher Education (MAHE), International Journal of Advanced Research (IJAR), ISSN 2320-5407.
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