Immunohistochemical Study of p53 and bcl-2 Expression in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma
- The Tamil Nadu Dr. M.G.R. Medical University
Thesis details
- Submitted by
- Dr. Karanam Badari Rao
- University
- The Tamil Nadu Dr. M.G.R. Medical University
- dr.badarirao@gmail.com
- Supervisor
- Dr. K. Ranganathan
- Year of award
- 2006
- Awards
- MASTER OF DENTAL SURGERY
Summary of Thesis
Oral squamous cell carcinoma (OSCC) is one of the leading causes of cancer related deaths in India. Oral epithelial dysplasia has a high probability of developing into OSCC and the percentage of such progression is believed to be directly proportional to the severity of dysplastic changes. Many biomarkers have been studied in the past to define the genetic progression model for OSCC. The most frequently studied marker is a tumor suppressor gene p53 and its aberrant protein expression is a well documented event in the development of OSCC. The protein expression of anti-apoptotic gene bcl-2 is believed to occur early in the process of oral carcinogenesis. This study aims to assess the immunohistochemical expression of p53 and bcl-2 in oral epithelial dysplasia and OSCC.
Thesis chapter scheme
1. Introduction 2. Aims and Objectives 3. Review of Literature 4. Materials and Methods 5. Results 6. Tables and Graphs 7. Photomicrographs 8. Discussion 9. Summary and Conclusion 10. Bibliography
How to Cite This Thesis
Dr. Karanam Badari Rao (2026); Immunohistochemical Study of p53 and bcl-2 Expression in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma, The Tamil Nadu Dr. M.G.R. Medical University, International Journal of Advanced Research (IJAR), ISSN 2320-5407.
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